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Tamiflu and swine flu

The influenza virus (e.g swine flu) has a gene that is responsible for making a protein called neuraminidase which helps the virus to escape the cell it has just infected so it can attack another cell in the body. Tamiflu is a drug that blocks the action of neuraminidase and so inhibits the spread of flu virus from one cell to another. Tamiflu has to be taken early on in the course of an infection to stand a good chance of working well. It can also be taken prophylactically to limit the spread of virus in the body.

Tamiflu is the trade name for the antiviral drug Oseltamivir. According to Wikipedia, Oseltamivir is "an antiviral drug, a neuraminidase inhibitor used in the treatment and prophylaxis of both influenza A and influenza B. Oseltamivir was the first orally active neuraminidase inhibitor commercially developed. It was developed by Gilead Sciences and is currently marketed by Hoffman-La Roche (Roche) under the trade name Tamiflu®."

Oseltamivir is indicated for the treatment and prevention of infections due to influenza A and B virus in people at least one year of age. The usual adult dosage for treatment of influenza is 75 mg twice daily for 5 days, beginning within 2 days of the appearance of symptoms and with decreased doses for children and patients with renal impairment. Oseltamivir may be given as a preventive measure either during a community outbreak of swine flu or following close contact with an infected individual.

Standard prophylactic dosage is 75 mg once daily for patients aged 13 and older, which has been shown to be safe and effective for up to six weeks. The importance of early treatment of swine flu is that the NA protein inhibition is more effective within the first 48 hours. If the virus has replicated and infected many cells the effectiveness of this medication will be severely diminished, especially over time.

Some people experience side effects after taking Tamiflu. For more news and information on this subject please see our "Side effects of Tamiflu" page.

Roche may be establishing partnerships around the world to increase Tamiflu production, but experts suggest that if--or when--a pandemic breaks out, it may be nearly impossible to acquire the drug.

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tamiflu - Google News
Thu, 29 Jul 2010 01:53:24 GMT+00:00

KMC roped in to tackle swine flu menace
Times of India
The experts at the meeting recommended a single dose of Tamiflu for 10 days for those who have come in close contact of any swine flu patient. ...

and more »
Thu, 22 Jul 2010 06:03:10 GMT+00:00

France24

Roche Profit Rises 58% on Lower Integration Costs
Bloomberg
Sales in the pharmaceutical unit fell 2.3 percent in the quarter, dragged down by lower revenue from the antiviral Tamiflu. “The results are not really that ...
Earnings WatchWall Street Journal
Roche net income climbs 8%; confirms outlookMarketWatch
Roche earnings sharply upAFP
RTT News -Pharma Times
all 186 news articles »
Wed, 28 Jul 2010 20:10:36 GMT+00:00

89 students fall prey to swine flu infection
Times of India
A total of 1112 people were also administered Tamiflu after screening on Tuesday. Most of them were suffering from symptoms like fever, sore throat and mild ...

and more »
Wed, 28 Jul 2010 20:13:51 GMT+00:00

Indian Express

Malaria, swine flu kill 1 each in Mumbai
Daily News & Analysis
On the other hand, the pregnant woman, who died of swine flu on Tuesday, had lost her baby two days ago in her womb after she was administered Tamiflu. ...
Slum-dweller succumbs to swine fluHindustan Times

all 12 news articles »
Wed, 28 Jul 2010 08:38:26 GMT+00:00

Swine flu-linked death referred to coroner
Stuff.co.nz
During her time in hospital, Ms Heng was sedated, put on a ventilator to help her breathe, given swine flu drug Tamiflu, antibiotics for other possible ...

and more »
Wed, 28 Jul 2010 17:25:01 GMT+00:00

Swine flu toll rises to four in Kolhapur district
Daily News & Analysis
Health Department started treating them by giving Tamiflu tablets. From the last year's Swine Flue outbreak, 4353 people were examined in Kolhapur district. ...

and more »
Wed, 28 Jul 2010 11:20:56 GMT+00:00

MedIndia

Swine flu kills 2 more in Delhi
TheMedGuru
Measures like sprucing up hospitals, stocking up on Tamiflu, and launching programs aimed at generating awareness about detection and prevention of swine ...
43 affected by swine flu in PuneArab News
Swine flu kills pregnant womanTopNews Arab Emirates
Two Rounds Of Sex A Week Prevents Side Effects Of H1N1 VaccinePeace FM Online
Times of India -Helium -Hindustan Times
all 146 news articles »
Wed, 28 Jul 2010 07:37:03 GMT+00:00

Herald Scotland

Scottish News: Paramedic delay blamed by husband over swine flu death
Scottish Daily Record
They told the 31-year-old's estranged husband Ricky they did not believe she had swine flu and did not prescribe the controversial drug Tamiflu. ...
Husband Claims Swine Flu Infected Wife Could Have Survived If Hospitalised SoonerVisit Bulgaria
Swine flu mother 'left to die'Express.co.uk
Swine flu victim's care criticised at Reading inquestBBC News
Herald Scotland
all 14 news articles »
Mon, 26 Jul 2010 16:15:28 GMT+00:00

H1N1 raises its head again
Times of India
She had grade 3 symptoms and we started her on Tamiflu even before getting the results," said a doctor at the hospital. The other two patients, ...

and more »
Thu, 22 Jul 2010 16:59:40 GMT+00:00

Sunday Star Times

Data back Tamiflu to slow flu spread
Emerging Health Threats Forum
Now research from the USA published this week in BMC Infectious Diseases 1 suggests that the drug Tamiflu (oseltamivir) was effective in reducing secondary ...
Four more H1N1 cases in cityTimes of India
Flu expert linked to drug firmsSunday Star Times
Vaccinations Against Influenza Strongly Encouraged For High Risk GroupsVoxy

all 57 news articles »

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